Sarah George, M.D., Associate Professor of Infectious Diseases, has received a grant from the National Institute of Allergy and Infectious Diseases at the NIH to study an investigational vaccine for yellow fever.

Yellow fever, a flavivirus like the Zika virus, is also spread by the Aedes mosquito. The current vaccine contains a weakened strain of the live virus and can therefore cause health problems for those who most need it, including infants and those with weakened immune systems. The George lab will conduct a clinical trial on a new vaccine for yellow fever that uses a modified version of the smallpox vaccine to deliver the yellow fever proteins to cells, thus stimulating an immune response. The vaccine will be tested for safety as well as efficiency of immune response.

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