Thomas Burris, Ph.D., Professor and Chair of Pharmacology and Physiology, and Colin Flaveny, Ph.D., Assistant Professor of Pharmacology and Physiology, published a paper in Molecular Metabolism detailing studies on the role of the nuclear receptor, REV-ERB, in muscle regeneration.
Dr. Burris previously published research showing that REV-ERB plays a role in lowering LDL cholesterol and also helps regulate internal clocks in mammals. This study showed that REV-ERB has differing roles in the different stages of muscle cell development, making it a key target for acceleration of muscle regeneration after traumatic injuries such as congestive heart failure, burns, cancer, and chronic obstructive pulmonary disease. Their research could lead to novel therapies for recovering patients.
For more information, read the full article in Newslink.