Daniela Salvemini, Ph.D., Professor of Pharmacology & Physiology, and her research group received two separate grants from the National Institutes of Health.

The first R01 grant will study chemotherapy-induced cognitive impairment (CICI), which is a serious side effect of some cancer treatments. CICI or “chemo-brain” is most commonly seen after treatment with platinum-based and anthracyclin chemotherapy drugs, widely used to treat head and neck, testicular, colon, breast, ovarian, and non-small cell lung cancers. CICI causes cognitive impairments such as memory problems, decreased attention span, and decreased processing speed, and symptoms often persist well after treatment is completed. With increasing numbers of cancer patients and survivors, CICI is quickly becoming a public health concern.

The second R01 grant aims to research ways to minimize the debilitating side effects of opioid drugs used to treat extreme pain caused by some cancers and cancer treatments, as well as decreasing development of tolerance and dependence to opioids. This grant will build on Dr. Salvemini’s previous work in this area.

For more information, read the full article in Newslink.